Solution to measurement uncertainty challenge

Solution to phenylbutazone purity challenge.

In the last 15 years NMR has become a reference technique for the determination of purity for organic standards containing NMR active nuclei [1, 2]. The puzzle proposed for this Analytical Challenge was focused on the use of 1H-NMR for the characterization of a phenylbutazone standard. Such material was purchased from Sigma-Aldrich and analyzed in parallel by HPLC-UV and 1H-NMR. Initially, appl...

Solution to spectroscopy challenge 8.

Malic acid was first isolated by Carl Wilhelm Scheele from apple juice in 1785. Scheele was born in 1742 in Stralsund. The German seaport of Stralsund is situated on the southern coast of a sound of the Baltic Sea that separates the island of Rügen from the mainland. This small town remained under Swedish control until 1815, when it became a part of the Prussian Province of Pomerania. Thus, Sch...

Solution to half-titration challenge.

Measurement Uncertainty: Reply to Critics

In a recent publication [PRL 111, 160405 (2013)] we proved a version of Heisenberg’s errordisturbance tradeoff. This result was in apparent contradiction to claims by Ozawa of having refuted these ideas of Heisenberg. In a direct reaction [arXiv:1308.3540] Ozawa has called our work groundless, and has claimed to have found both a counterexample and an error in our proof. Here we answer to these...

Evaluating Predictive Uncertainty Challenge

This Chapter presents the PASCAL Evaluating Predictive Uncertainty Challenge, introduces the contributed Chapters by the participants who obtained outstanding results, and provides a discussion with some lessons to be learnt. The Challenge was set up to evaluate the ability of Machine Learning algorithms to provide good “probabilistic predictions”, rather than just the usual “point predictions”...